中国麻风皮肤病杂志 ›› 2025, Vol. 41 ›› Issue (9): 682-684.doi: 10.12144/zgmfskin202509682

• 病例报告 • 上一篇    下一篇

托法替布治疗顽固性玫瑰痤疮一例

曲芃1,2,刘永霞1,2,王广进1,2   

  1. 1 山东第一医科大学附属皮肤病医院，山东济南，250022；2山东省皮肤病性病防治研究所，山东济南，250022
  • 出版日期:2025-09-15 发布日期:2025-09-08

Tofacitinib in the treatment of refractory rosacea: a case report

QU Peng1,2, LIU Yongxia1,2, WANG Guangjin1,2   

  1. 1 Dermatology Hospital of Shandong First Medical University, Jinan 250022,China; 2 Shandong Provincial Institute of Dermatology and Venereology, Shandong Academy of Medical Sciences, Jinan 250022, China
  • Online:2025-09-15 Published:2025-09-08

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摘要： 玫瑰痤疮是一种慢性炎症性皮肤病，主要表现为面部阵发性潮红、持续性红斑、丘疹和脓疱形成、毛细血管扩张、鼻部肥大等。临床上对于顽固性玫瑰痤疮，传统的治疗方法如口服抗生素和局部用药效果往往有限，病情容易反复。本文报道了口服托法替布治疗顽固性玫瑰痤疮一例并对相关文献进行复习。

关键词: 玫瑰痤疮, 托法替布

Abstract: Rosacea is a chronic inflammatory skin disease primarily characterized by episodic facial flushing, persistent erythema, papule and pustule formation, telangiectasia, and nasal hypertrophy. Clinically, traditional treatments for refractory rosacea-such as oral antibiotics and topical medications-often yield limited efficacy and are associated with a high tendency for recurrence. In this paper, we report a case of refractory rosacea treated with tofacitinib and review the relevant literature.

Key words: rosacea, tofacitinib