中国麻风皮肤病杂志 ›› 2021, Vol. 37 ›› Issue (12): 783-786.doi: 10.12144/zgmfskin202112783

• 临床研究 • 上一篇    下一篇

司库奇尤单抗成功治疗毛发红糠疹一例并文献复习

陈佳林,刘国艳,周桂芝,田洪青   

  1. 山东第一医科大学附属皮肤病医院(山东省皮肤病医院)，山东省皮肤病性病防治研究所，济南，250022
  • 出版日期:2021-12-15 发布日期:2021-09-29
  • 通讯作者: 田洪青，E-mail: tianhq2006@126.com

Pityriasis rubra pilaris successfully treated with secukinumab: a case report and literature review

CHEN Jialin, LIU Guoyan, ZHOU Guizhi, TIAN Hongqing   

  1. Shandong Provincial Hospital for Skin Diseases & Shandong Provincial Institute of Dermatology and Venereology, Shandong First Medical University & Shandong Academy of Medical Sciences, Jinan 250022, China
  • Online:2021-12-15 Published:2021-09-29
  • Contact: TIAN Hongqing, E-mail: tianhq2006@126.com

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摘要： 毛发红糠疹常规治疗包括系统应用维A酸类药物、甲氨蝶呤、环孢素，外用糖皮质激素以及物理治疗等，但效果并不理想。近年来，国外有应用司库奇尤单抗治疗毛发红糠疹的病例报道，且取得了较好的疗效，但国内未见相关报道。本文报道司库奇尤单抗成功治疗毛发红糠疹一例并对相关文献进行复习。

关键词: 毛发红糠疹, 治疗, 生物制剂, 司库奇尤单抗

Abstract: The efficacy of traditional treatment for pityriasis rubra pilaris, including retinoids, methotrexate, cyclosporine, topical glucocorticoids, and physical therapy, is not satisfactory. The foreign research reported secukinumab was used for treatment of pityriasis rubra pilaris and obtained good efficacy, but there was no report in China. We report a case with pityriasis rubra pilaris successfully treated with secukinumab and review the related literature review. 

Key words: pityriasis rubra pilaris, treatment, biological agents, secukinumab