中国麻风皮肤病杂志 ›› 2023, Vol. 39 ›› Issue (7): 512-515.doi: 10.12144/zgmfskin202307512

• 病例报告 • 上一篇    下一篇

面部肿胀性红斑狼疮继发龟分枝杆菌感染一例

彭一然,孙乐乐,暴芳芳,周桂芝,卢宪梅,刘永霞,刘红,张福仁   

  1. 山东第一医科大学附属皮肤病医院（山东省皮肤病医院），山东省皮肤病性病防治研究所，山东济南，250022
  • 出版日期:2023-07-15 发布日期:2023-07-05

Facial tumescent lupus erythematosus secondary with Mycobacterium chelonae infection: a case report

PENG Yiran, SUN Lele, BAO Fangfang, ZHOU Guizhi, LU Xianmei, LIU Yongxia, LIU Hong, ZHANG Furen   

  1. Shandong Provincial Hospital for Skin Diseases & Shandong Provincial Institute of Dermatology and Venerology, Shandong First Medical University & Shandong Academy of Medical Sciences, Jinan 250022, China
  • Online:2023-07-15 Published:2023-07-05

PDF (PC)

58

摘要： 龟分枝杆菌感染可继发于外科手术操作、外伤等，也可能与使用免疫抑制药物相关。临床表现与病理表现缺乏特异性，需抗生素联合足疗程治疗。本文报道一例面部肿胀性红斑狼疮，治疗数天后面部原皮疹部位继发红斑、丘疹、脓疱，通过皮肤组织活检、qPCR测序确诊龟分枝杆菌感染，患者经克拉霉素、利奈唑胺药物联合治疗后好转。

关键词: 非典型分枝杆菌, 龟分枝杆菌, 肉芽肿, 测序, 克拉霉素, 利奈唑胺

Abstract: Mycobacterium chelae infection can be occurred after surgery or trauma, and may also be related to the use of immunosuppressive medicine. The manifestations lacks of specificity. It requires a combination of antibiotics and a full course of treatment. We report a case of facial tumescent lupus erythematosus complicated with Mycobacterium chelae infection. The diagnosis was confirmed by skin biopsy and qPCR sequencing. The patient was cured by clarithromycin and linezolid.

Key words: Non-tuberculous Mycobacteria, Mycobacterium chelae, granuloma, sequencing, clarithromycin, linezolid