China Journal of Leprosy and Skin Diseases ›› 2019, Vol. 35 ›› Issue (6): 338-341.doi: 10.12144/zgmfskin201906338

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Expression of Livin and Caspase-3 in the lesions of incipient condyloma acuminatum

LIN Li1, WANG Jun2, QIN Xiaoming1   

  1. 1.Department of Dermatology and STD,The Second Affiliated Hospital of Wannan Medical College,Wuhu 241001,China;2.Department of Dermatology and STD,The First Affiliated Hospital of Wannan Medical College,Wuhu 241001,China
  • Online:2019-06-15 Published:2019-06-06
  • Contact: WANG Jun,E-mail:13956203226@163.com

Abstract: Objective: To determine  the expression of Livin and Caspase-3 in the lesions of incipient condyloma acuminatum. Methods: The expression of Livin and Caspase-3 in the lesions of incipient condyloma acuminatum and normal prepuce tissues was detected by Streptavidin-peroxidase. Results: The positivity rates of Livin and Caspase-3 in the incipient condyloma acuminatum and normal prepuce were 76.67% and 43.33%,  25.00% and 70.00%. There was no correlation between the expression intensity of Livin and Caspase-3 in the incipient condyloma acuminatum group (r=0.238,P>0.05).Conclusion: There is high expression of Livin and low expression of Caspase-3 in the lesions of incipient condyloma acuminatum. Both may be involved in the development of condyloma acuminatum.

Key words: condyloma acuminatum, apoptosis, Streptavidin-peroxidase, Livin, Caspase-3