Abstract: Objective: To analyze the related factors of psoriasis complicated with type 2 diabetes. Methods: The inpatients with psoriasis in Shandong Provincial Hospital for Skin Diseases from 2008 to 2016 were collected and as the case group 1, and healthy physical examinees were as the control group 1. Compare the differences in gender, age, and fasting blood glucose values between the two groups. Then the patients in the case group 1 were divided into the case group 2 and the control group 2 according to whether with type 2 diabetes or not. The information of gender, hospitalization frequency and days, body surface area of lesions, PASI score were compared. Results: There were 570 patients in the case group 1 including 164 (28.77%) with type 2 diabetes and 4513 controls in the control group 1 including 164 (28.77%) with type 2 diabetes. In the case group 1, the morbidity of the male and female patients with type 2 diabetes was 31.5% and 19.2%, with a significant difference (P<0.05). There were 164 and 406 cases in the case group 2 and control group 2. Compared to the control group 2, the onset age was younger, the course was longer and the hospitalization frequency was more in the case group 2, with significant differences (Ps<0.05). The proportion of smokers in the case group 2 was 43.9%, which was higher than those in the control group 2, with a significant difference (P<0.05). There was no significant difference of body surface area of lesions and PASI score between the case group 2 and the control group 2 (Ps>0.05).  Conclusion: The incidence of type 2 diabetes in the patients of psoriasis is higher than that in healthy controls. The gender, age and smoking history may be related to the psoriasis complicated with type 2 diabetes. 

Key words: psoriasis, type 2 diabetes