Abstract: Objective: To explore the related factors of dermatomyositis (DM) complicated with tumors in adults. Methods: A retrospective analysis of adult patients with DM in the department of dermatology of the First Affiliated Hospital of Zhengzhou University from January 2016 to December 2018 was performed. A total of 16 indicators of their clinical characteristics and laboratory tests were statistically analyzed. Results: Among 114 adult patients with DM, 21 were associated with tumors, with a detection rate of 18.4%, of which lung cancer (6 patients, 28.57%) was the most common. The univariate analysis between the 93 patients with DM and 21 with DM complicated with tumors showed that the age, gender, dysphagia, albumin level and the erythrocyte sedimentation rate was significantly different (Ps<0.05) . Incorporating the statistically significant indicators of the above univariate analysis into the multivariate Logistic analysis showed that gender of male and ESR are risk factors that affect adult DM with tumors. Conclusion: We should consider male patients with DM or ESR≥35 mm/h as risk factors for DM-associated tumors in adults, and strengthen early tumor screening for DM.

Key words: dermatomyositis, malignant tumor, risk factors