先天自愈性朗格汉斯组织细胞增生症一例

doi:10.12144/zgmfskin202301037

Abstract

Abstract: A one-month-old girl presented with red papules and scabs on her head and face gradually increased for 1 month. Dermatological examination showed soybean to pea sized papules, papulovesicles, scabs on his scalp, forehead, trunk and limbs. A few of the rashes have scales, which were not easily to scrape. Histopathological examination revealed edema between epidermal cells, mononuclear cell migration, basal cell liquefaction and degeneration, more mononuclear cell infiltration in the superficial and middle dermis, with large nucleus and rich cytoplasm. DIF: negative for IgG, C3, IgM, IgA between epidermal cells and basement membrane. Immunohistochemistry: weakly positive for CD1a, S100, CD68, positive for Langerin. No treatment was given. The lesions dissipated and no new rash occurred after 1 month follow-up.

Key words: Langerhans cell histiocytosis, self-healing, congenital

WANG Na, WU Mei, ZHOU Guizhi, YANG Qing. Congenital self-healing Langerhans cell histiocytosis: a case report[J].China Journal of Leprosy and Skin Diseases, 2023, 39(1): 37-39.

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Congenital self-healing Langerhans cell histiocytosis: a case report

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