Abstract: Tranexamic acid has been increasingly used in dermatology in recent years. The drug is mainly administrated orally at low doses with good safety, and the most common adverse reactions are gastrointestinal discomfort and menstrual irregularity. However, long-term systemic application of tranexamic acid can lead to a variety of adverse reactions, such as thrombosis, hepatic and kidney impairment, visual defects, etc. Therefore, regularly monitoring blood coagulation function, D-dimer, hepatic and kidney function and other related indicators is necessary when taking tranexamic acid for a long time, so as to detect and manage adverse reactions timely and ensure drug safety.

Key words: tranexamic acid, adverse reaction, thrombosis, management