Abstract: Neonatal autoimmune bullous diseases are relatively rare, usually occurring soon after birth. Clinically, they are mostly characterized by erythema, blisters, erosion and other lesions on normal skin or mucous membranes. Most of these diseases are self-limiting with a good prognosis, while some children may have varying degrees of residual mucosal damage, and a few may die due to complications, which requires early intervention and active treatment by clinicians. This article reviews the pathogenesis, clinical manifestations, differential diagnosis, treatment and perinatal management of these diseases, aiming to improve the understanding of the disease.

Key words: neonatal autoimmune blistering diseases, pemphigus vulgaris, bullous pemphigoid, linear IgA bullous dermatosis