China Journal of Leprosy and Skin Diseases ›› 2024, Vol. 40 ›› Issue (12): 855-858.doi: 10.12144/zgmfskin202412855

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Nonbullous pemphigoid: four cases report and literature review

SHAO Yuling1,2*, WANG Na1,2*, YU Changping1,2, LIU Yongxia1,2, ZHOU Guizhi1,2, YANG Qing1,2   

  1. 1 Hospital for Skin Diseases, Shandong First Medical University, Jinan 250022, China; 2 Shandong Provincial Institute of Dermatology and Venereology, Shandong Academy of Medical Sciences, Jinan 250022, China *Co-first author
  • Online:2024-12-15 Published:2024-10-31

Abstract: Nonbullous pemphigoid is a rare type of bullous pemphigoid, which is easily misdiagnosed and missed because its clinical presentation lacks the tense blisters or macules typical of pemphigus herpetiformis. We reported four cases of nonbullous pemphigoid misdiagnosed as eczema or prurigo nodularis and reviewed the related literature. The four patients presented with erythema, papules, nodules, accompanied by pruritus and showed positive of anti-BP180 antibodies and anti-BP230 antibodies. After the patient was given glucocorticoids, niacinamide, and tripterygium glycoside, their condition improved significantly.

Key words: nonbullous pemphigoid