Abstract: Bullous scabies (BS) is a rare clinical manifestation of scabies that is easily misdiagnosed. In this paper, we report three patients with BS who were previously misdiagnosed and search the related literature in Wanfang and PubMed database, then analyze the demographic information, pathogenesis, clinical manifestations, pathological characteristics, and treatment of the disease. It is found that BS is more common in the elderly population and male patients, about one third of the patients had a history of misdiagnosis, and three quarters of the patients had no remission or further progression after receiving glucocorticoid treatment. It is suggested that dermatologists should improve their understanding and diagnosis of this disease and the treatment should be cautious with the use of glucocorticoids.

Key words: bullous scabies, sarcoptic mite, glucocorticoid, bullous pemphigoid