China Journal of Leprosy and Skin Diseases ›› 2016, Vol. 32 ›› Issue (2): 93-95.

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Herpetiform pemphigus: 3 cases report

DU Tiantian, YANG Baoqi, WANG Guangjin, ZHOU Guizhi, LIU Hong, ZHANG Furen.   

  1. 1. Shandong Provincial Institute of Dermatology and Venereology, Jinan 250022, China; 2. School of Medical and Life Science, University of Ji'nan,Jinan 250062,China
  • Online:2016-02-15 Published:2018-12-18
  • Contact: ZHANG Furen. Email:zhangfuren@hotmail.com

Abstract: Three patients with herpetiform pemphigus were presented. There were two males and one female, with an average age of 67 years. The main clinical manifestations were erythema and blisters scattered over the body. Biopsy showed intraepidermal blisters and the infiltration of eosinophilic granulocyte. Direct immunofluorescence showed IgG deposition in epidermal cells. Indirect immunofluorescence in one patient showed positive antibody to pemphigus, with a titer of 1:80. Dapsone and glucocorticoid were effective.

Key words: pemphigus herpetiformis, dapsone, glucocorticoid