Abstract: A case of erythema elevatum diutinum treated with dapsone monotherapy was reported and the related literature was reviewed. An 80-year-old female presented with reddish-brown patches on the palms, buttocks, lower extremities and plantar for half a year. Histopathological examination showed hyperkeratosis, dyskeratosis, mild acanthosis, fibrin-like degeneration of vascular wall in the superficial and middle dermis, mild infiltration of neutrophils around blood vessels, infiltration of lymphocytes and basophilic degeneration of local collagen fibers. The diagnosis of erythema elevatum diutinum was made. The patient was treated with oral dapsone 100 mg, once a day and the skin lesions were significantly improved after 3 months of follow-up. 

Key words: erythema elevatum diutinum, dapsone