Abstract: Objective: To determine the relationship between the mean platelet volume (MPV) level and disease severity of psoriasis vulgaris. Methods: The level of MPV was detected in 150 patients and 50 healthy controls. The PASI of patients was clinically assessed. Results: Platelet distribution width and MPV were significantly higher in the patients than in controls. There was positive correlation between PASI and MPV and MPV level. The level of MPV was significantly decreased after treatment. Conclusion: MPV is positively correlated with the severity of psoriasis.

Key words: mean platelet volume, psoriasis