中国麻风皮肤病杂志 ›› 2019, Vol. 35 ›› Issue (2): 73-76.doi: 10.12144/zgmfskin201902073

• 论著 • 上一篇    下一篇

富血小板血浆治疗麻风溃疡三例

于德宝1,2  刘岩松2  阮振强2  王大见 张福仁3   

  1. 1济南大学 山东省医学科学院医学与生命科学学院,济南,250001
    2济南市皮肤病防治院,济南,250001
    3山东省皮肤病医院,济南,250022
  • 出版日期:2019-02-20 发布日期:2019-03-07
  • 通讯作者: 张福仁,E-mail:zhangfuren@hotmail.com

Platelet-rich plasma for treating ulcers in 3 patients with leprosy

YU Debao1,2, LIU Yansong2, RUAN Zhenqiang2, WANG Dajian2,ZHANG Furen3   

  1. 1.School of Medicine and Life Sciences, University of Jinan-Shandong Academy of Medical Sciences,Jinan 250001,China;  2.Jinan Dermatosis Prevention and Control Hospital, Jinan 250001,China;  3.Shandong Provincial Hospital for Skin Diseases, Jinan 250022,China
  • Online:2019-02-20 Published:2019-03-07
  • Contact: ZAHNG Furen, E-mail:zhangfuren@hotmail.com

摘要: 目的:评价自体富血小板血浆(platelet-rich plasma,PRP)治疗麻风溃疡的疗效。方法:采用麻风3例患者的自体血10~20mL,经2次离心后,获取高浓度的富血小板血浆,在麻风溃疡周边及溃疡面内注射治疗,观察不同治疗次数情况下,麻风溃疡的愈合时间、愈合面积等情况。结果:3例患者中,2例患者的3处溃疡得到治愈,1例患者的溃疡面积缩小了95%。结论:PRP疗法治疗麻风溃疡简单、安全、有效。

关键词: 富血小板血浆, 麻风, 溃疡

Abstract: Objective: To assess the efficacy of autologous platelet-rich plasma (PRP)  in the treatment of leprosy soles ulcer. 
Methods: 10-20mL autologous blood was obtained from three leprosy patients in each, and then, high-concentration platelet-rich plasma was obtained after centrifugation. The blood was injected into the tissues around foot ulcer and the ulcer surface. Results: Of 3 cases, ulcers  were curred in 2 cases and significant improvement in one (95% reduction of the foot ulcer). Conclusion: PRP therapy is a simple, safe and effective methods for treating leprosy ulcers.

Key words: platelet-rich plasma, leprosy, ulcer