中国麻风皮肤病杂志 ›› 2024, Vol. 40 ›› Issue (4): 267-270.doi: 10.12144/zgmfskin202404267

• 临床研究 • 上一篇    下一篇

595 nm PDL与1064 nm Nd:YAG激光联合治疗婴儿尿布区溃疡性血管瘤疗效分析

曹蓉,柴圆圆,钱华   

  1. 苏州大学附属儿童医院，江苏苏州215025
  • 出版日期:2024-04-15 发布日期:2024-03-26

Effect of 595 nm PDL combined with 1064 nm Nd：YAG in the treatment of ulcerated infantile hemangiomas in the diaper area

CAO Rong, CHAI Yuanyuan, QIAN Hua   

  1. Children's Hospital of Soochow University, Suzhou 215025, China
  • Online:2024-04-15 Published:2024-03-26

PDF (PC)

14

摘要： 目的：评价595 nm PDL与1064 nm Nd:YAG激光联合治疗婴儿尿布区溃疡性血管瘤的疗效及安全性。方法：针对尿布区域溃疡性血管瘤患者，溃疡创面采用PDL治疗，光斑直径7 mm，脉宽1.5 ms，能量密度7~9 J/cm2，每周重复治疗1次。非溃疡部分采用PDL和1064 nm Nd:YAG激光模式联合治疗。激光参数如下，PDL采用7 mm光斑，脉宽6 ms，能量密度12 J/cm2，Nd:YAG脉宽45 ms，能量密度30~40 J/cm2，每两周进行1次。结果：共治疗32例患者，溃疡面治疗1周后，有9例患者开始愈合，治疗2周后进行随访，有28例患者溃疡面逐渐愈合。非溃疡处皮损经2~6次治疗后，29例患者皮疹消退60%以上。3例溃疡面较大者出现明显瘢痕。结论：595 nm PDL与1064 nm Nd:YAG激光联合治疗婴儿尿布区溃疡性血管瘤安全有效。

关键词: 溃疡性血管瘤, 尿布区, 婴儿, 595 nm PDL, 1064 nm Nd:YAG

Abstract: Objective: To evaluate the efficacy and safety of 595 nm PDL combined with 1064 nm Nd:YAG laser in the treatment of ulcerated infantile hemangiomas in the diaper area. Methods: The patients with ulcerated infantile hemangiomas in the diaper area were treated. Ulcers were treated with PDL (spot diameter 7 mm，pulse width 1.5 ms，energy density 7-9 J/cm2) every week. The remaining hemangioma excluding the ulcerated portion were treated with PDL and Nd:YAG laser (PDL, spot diameter 7 mm，pulse width 6 ms，energy density 12 J/cm2; Nd:YAG pulse width 45 ms，energy density 30-40 J/cm2) at two-week intervals. Results: Thirty-two patients were collected. Ulcerative lesions in nine patients healed within one week after the first treatment and twenty-eight patients healed within two weeks following the second treatment. The remaining hemangioma in twenty-nine patients subsided by more than 60% after two to six treatments. Obvious scarring occurred in three patients with large ulcerated lesions. Conclusions: The treatment of 595 nm PDL combined 1064 nm Nd:YAG laser is effective and safe in ulcerated infantile hemangiomas in the diaper area.

Key words: ulcerated hemangiomas, diaper area, infant, 595 nm PDL, 1064 nm Nd:YAG