中国麻风皮肤病杂志 ›› 2024, Vol. 40 ›› Issue (7): 514-518.doi: 10.12144/zgmfskin202407514

• 综述 • 上一篇    下一篇

天疱疮复发相关因素研究进展

唐冬梅1,葛世亮2,闫雨柔1,李晓岚1   

  1. 1昆明医科大学第二附属医院皮肤科，云南昆明，650000；2昆明医科大学第二附属医院烧伤科，云南昆明，650000
  • 出版日期:2024-07-15 发布日期:2024-06-12

Update of factors related to pemphigus relapse

TANG Dongmei1, GE Shiliang2, YAN Yurou1, LI Xiaolan1   

  1. 1 Department of Dermatology, The Second Affiliated Hospital of Kunming Medical University, Kunming 650000, China; 2 Department of Burn, The Second Affiliated Hospital of Kunming Medical University, Kunming 650000, China
  • Online:2024-07-15 Published:2024-06-12

PDF (PC)

44

摘要： 天疱疮是一种危及生命的慢性自身免疫性疱病，糖皮质激素和免疫抑制剂是目前主要的治疗手段。目前随着利妥昔单抗的使用，天疱疮的缓解率明显提高，但在诸多因素影响下，复发仍然常见，且严重影响了患者的生命质量。本文就天疱疮复发相关因素的最新研究进行综述。

关键词: 天疱疮, 抗桥粒芯蛋白, 复发因素, 利妥昔单抗

Abstract: Pemphigus is a life-threatening chronic autoimmune blistering disease, and glucocorticoids and immunosuppressive agents are common treatment. With the use of rituximab (RTX), there has been a significant improvement in the remission rate of pemphigus. However, relapses remain common due to various influencing factors and seriously affect the quality of patients. The latest research on factors associated with pemphigus relapse are reviewed in this paper provides.

Key words: pemphigus, anti-desmoglein, relapse factors, rituximab