中国麻风皮肤病杂志 ›› 2025, Vol. 41 ›› Issue (11): 829-835.doi: 10.12144/zgmfskin202511829

• 综述 • 上一篇    下一篇

痤疮药物治疗的研究进展

史希武,钱芳芳,潘霄汝,胡军,姚凤鸣   

  1. 安庆市立医院皮肤性病科,安徽安庆,246000
  • 出版日期:2025-11-15 发布日期:2025-11-11

Research progress on drug treatment of acne

SHI Xiwu, QIAN Fangfang, PAN Xiaoru, HU Jun, YAO Fengming   

  1. Department of Dermatology and Venereology, Anqing Municipal Hospital, Anqing 246000, China
  • Online:2025-11-15 Published:2025-11-11

摘要: 痤疮是一种门诊常见的累及毛囊皮脂腺的慢性炎症性疾病,皮损严重者易损容并对心理健康造成一定的危害。传统治疗药物如外用抗生素、维A酸类药物及口服抗生素、异维A酸、抗雄激素药物已在临床上广泛使用,但部分因不良反应多、疗程长及产生耐药性等诸多问题而不被患者所接受。本文综述了近年来痤疮药物治疗的研究进展,旨在为皮肤科医生提供更多的理论依据和治疗选择。

关键词: 痤疮, 药物治疗, 局部用药, 系统用药

Abstract: Acne is a common chronic inflammatory disease involving hair follicles and sebaceous glands in outpatient clinics. Patients with severe skin lesions are prone to facial disfigurement and may suffer certain psychological harms. Traditional therapeutic drugs such as topical antibiotics, retinoids, oral antibiotics, isotretinoin and androgen antagonists, have been widely used in clinical practice. However, some of the above drugs are not accepted by patients due to problems such as multiple side effects, long treatment courses and drug resistance. This article reviews the research progress on drug treatment of acne in recent years, which aims to provide more theoretical basis and treatment options for dermatologists.

Key words: acne, drug treatment, topical medication, systemic medication