中国麻风皮肤病杂志 ›› 2026, Vol. 42 ›› Issue (5): 369-371.doi: 10.12144/zgmfskin202605369

• 病例报告 • 上一篇    下一篇

异维A酸治疗面部多发皮脂腺增生一例

潘伟军1,丁笑笑2,3,周婧2,3,李芳谷2,3   

  1. 1江门市新会区第二人民医院皮肤科，广东江门，529100；2广东医科大学附属医院皮肤与性病科，广东湛江，524000；3广东医科大学第一临床医学院皮肤病与性病学教研室，广东湛江，524000
  • 出版日期:2026-05-15 发布日期:2026-05-12

Oral isotretinoin capsules in the treatment of multiple facial sebaceous hyperplasia: a case report

PAN Weijun1, DING Xiaoxiao2,3, ZHOU Jing2,3， LI Fanggu2,3   

  1. 1 Dermatology Department, Second People's Hospital of Xinhui District, Jiangmen City, Jiangmen 529100, China; 2 Department of Dermatology and Venereology, Affiliated Hospital of Guangdong Medical University, Zhanjiang 524000, China; 3 Teaching and Research Section of Dermatology and Venereology, The First Clinical Medical College of Guangdong Medical University, Zhanjiang 524000, China
  • Online:2026-05-15 Published:2026-05-12

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摘要： 目前关于口服异维A酸治疗皮脂腺增生的报道较少，本文报道一例采用低剂量异维A酸胶囊（0.4 mg/kg·d）治疗面部多发皮脂腺增生病例。患者治疗8周后，面部皮损即获显著改善，且仅出现轻度口唇干燥，提示口服异维A酸胶囊治疗皮脂腺增生是一种有效且相对安全的选择。

关键词: 皮脂腺增生, 多发, 异维A酸

Abstract: Reports on oral isotretinoin in the treatment of sebaceous hyperplasia are limited. Herein, we report a case of multiple facial sebaceous hyperplasia treated with low-dose isotretinoin capsules (0.4 mg/kg·d). After 8 weeks of treatment, the facial lesions showed significant improvement, with only mild cheilitis observed as an adverse reaction. This suggests that oral isotretinoin capsules represent an effective and relatively safe systemic therapeutic option for patients with multiple sebaceous hyperplasia.

Key words: sebaceous hyperplasia, multiple, isotretinoin