中国麻风皮肤病杂志 ›› 2017, Vol. 33 ›› Issue (8): 474-476.

• 论著 • 上一篇    下一篇

35例获得性反应性穿通性胶原病分析

刘永霞  王建文  周桂芝  陈声利  陈学超  卢宪梅   

  1. 山东省皮肤病性病防治研究所，济南，250022
  • 出版日期:2017-08-15 发布日期:2018-12-05
  • 通讯作者: 刘永霞，E-mail：liuyx_comeon@163.com

Clinical and pathological analyses of 35 cases with acquired reactive perforating collagenosis

LIU Yongxia, WANG Jianwen, ZHOU Guizhi, CHEN Shengli, CHEN Xuechao, LU Xianmei.   

  1. Shandong Provincial Institute of Dermatology and Venereology, Jinan 250022, China
  • Online:2017-08-15 Published:2018-12-05
  • Contact: LIU Yongxia, E-mail: liuyx_comeon@163.com

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摘要： 本文对2013-2016年我院35例获得性反应性穿通性胶原病临床资料和组织病理进行回顾性分析，其中男女比例为1∶1.19，平均发病年龄49.5岁，病程长短不一，临床皮损形态多样，组织病理均可见胶原纤维穿出表皮，20%患者伴有系统性疾病，临床误诊率为77%，最易误诊为结节性痒疹(13例次)和湿疹(10例次)。

关键词: 获得性反应性穿通性胶原病, 临床, 病理

Abstract: Clinical and pathological data of 35 cases with acquired reactive perforating collagenosis collected from 2013 to 2016 was retrospectively analyzed. The ratio of male to female was 1∶1.19. The average age at onset of the disease was 49.5 years. The duration of the disease was diverged significantly. The histopathology shows collagen fibers within the epidermis. Only 20% of the patients were found having systemic disease. The skin lesions were diverse. The misdiagnosis rate was 77% and the disease was most misdiagnosed as prurigo nodularis (13 times) and eczema (10 times).

Key words: acquired reactive perforating collagenosis, clinic, pathology