中国麻风皮肤病杂志 ›› 2025, Vol. 41 ›› Issue (1): 64-65.doi: 10.12144/zgmfskin202501064

• 病例报告 • 上一篇    下一篇

左足颗粒细胞瘤一例

张雪燕1,2，张铭凯1,2，曹楠1,2，陈声利1,2   

  1. 1山东第一医科大学附属皮肤病医院，山东济南，250022；2山东省皮肤病性病防治研究所，山东济南，250022
  • 出版日期:2025-01-15 发布日期:2024-12-23

Granulosa cell tumor on the left heel: a case report

ZHANG Xueyan1,2, ZHANG Mingkai1,2, CAO Nan1,2, CHEN Shengli1,2   

  1. 1 Hospital for Skin Diseases, Shandong First Medical University, Jinan 250022, China; 2 Shandong Provincial Institute of Dermatology and Venereology, Shandong Academy of Medical Sciences, Jinan 250022, China
  • Online:2025-01-15 Published:2024-12-23

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摘要： 颗粒细胞瘤（granular cell tumor，GCT）是一种罕见软组织肿瘤，临床皮损不典型，好发于头颈部，发生于足部者少见。本患者左足跟角质性斑块20年，组织病理示：真皮内见大圆形细胞排列成巢状，细胞核小、居中，胞质内见嗜酸性颗粒。免疫组化：S-100（+)、SOX10（+）、NSE（+）、CD68（+）。诊断为颗粒细胞瘤，予以手术切除。

关键词: 左足跟, 颗粒细胞瘤, 诊断

Abstract: Granular cell tumor (GCT) is a rare soft tissue tumor. The skin lesions are atypical and usually occur in the head and neck, but rarely on the feet. The patient presented with keratinous plaques on the left heel for 20 years. Histopathology showed large circular cells arranged in nests within the dermis，the nucleus is small and centered, acidophilic granules can be seen in the cytoplasm. Immunohistochemistry showed S-100（+）, SOX10（+）, NSE（+）, CD68（+). The patient was diagnosed with granulosa cell tumor and underwent surgical resection.

Key words: left heel, granulosa cell tumor, diagnosis