中国麻风皮肤病杂志 ›› 2026, Vol. 42 ›› Issue (9): 668-670.doi: 10.12144/zgmfskin202609668

• 病例报告 • 上一篇    下一篇

误诊为感染性肉芽肿的罕见指尖皮肤转移癌一例

范高远1,2*,李珍1,2*,刘永霞1,2,朱莉1,2,陈学超1,2,刘红1,2,张福仁1,2   

  1. 1山东第一医科大学附属皮肤病医院，山东济南，250022；2山东省皮肤病性病防治研究所，山东济南，250022 *共同第一作者
  • 出版日期:2026-09-15 发布日期:2026-09-02

Metastatic carcinoma of the fingertip skin misdiagnosed as infectious granuloma: a case report

FAN Gaoyuan1,2*, LI Zhen1,2*, LIU Yongxia1,2, ZHU Li1,2, CHEN Xuechao1,2, LIU Hong1,2, ZHANG Furen1,2   

  1. 1 Dermatology Hospital of Shandong First Medical University, Jinan 250022, China; 2 Shandong Provincial Institute of Dermatology and Venereology, Shandong Academy of Medical Sciences, Jinan 250022, China *Co-first authors
  • Online:2026-09-15 Published:2026-09-02

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摘要： 患者，男，59岁，外伤后左手中指出现红肿、糜烂、渗出，伴疼痛，外院初诊为感染性肉芽肿，给予氧氟沙星、米诺环素、特比萘芬治疗40天无好转。组织病理示真皮层存在大量团块状肿瘤细胞，免疫组化示CK7（+）、GATA3（+）、CK20（-），结合患者肾癌病史1年，诊断为皮肤转移癌，肾盂来源。患者未继续治疗，1个月后死亡。

关键词: 皮肤转移癌, 感染性肉芽肿

Abstract: A 59-year-old male patient presented with redness, erosion, exudation, and pain in the left middle finger after trauma. The initial diagnosis was infectious granuloma at another hospital and treated with ofloxacin, minocycline and terbinafine for 40 days, yet the lesions showed no improvement. Histopathological examination revealed a large number of nodular tumor cells in the dermis. Combined with immunohistochemical staining results of CK7 (+), GATA3 (+), CK20 (-) and the patient's one-year history of renal cell carcinoma, the diagnosis of skin metastatic carcinoma originating from the renal pelvis was made. The patient did not continue treatment and died one month later.

Key words: cutaneous metastatic carcinoma, infectious granuloma