China Journal of Leprosy and Skin Diseases ›› 2022, Vol. 38 ›› Issue (11): 816-818.doi: 10.12144/zgmfskin202211816

• Case Reports • Previous Articles     Next Articles

Cutaneous Rosai-Dorfman disease successfully treated with thalidomide: a case report

TAN Yan, QIAN Yuetong, MA Donglai   

  1. Department of Dermatology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences,National Clinical Research Center for Skin and Immune Diseases, Beijing 100730, China
  • Online:2022-11-15 Published:2022-10-26

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Abstract: A 53-year-old female presented with a 1-year history of dark-red, yellowish nodules and plaques on her face. Histopathology revealed infiltration of histiocytes, lymphoplasma cell and neutrophils, and emperipolesis was observed. These histiocytes were positive for S-100 and negative for CD68, CD1a. The diagnosis of cutaneous Rosai-Dorfman disease was made. The patient was treated with thalidomide for six months and the lesion was improved significantly.

Key words: cutaneous Rosai-Dorfman disease, thalidomide