Abstract: Facial multiple seborrheic keratosis are usually misdiagnosed as verruca plana in puber. The data of 35 patients with facial multiple seborrheic keratosis was analyzed. The clinical features of 35 patients with facial multiple seborrheic keratosis are as follows: ① The size and morphology were symmetrical. ② The patients was often accompanied by skin tags. ③The facial skin rash was often distributed on the bucca, the lateral eyes, the forehead and the pars zygomatica. ④ There was no auto-inoculation's phenomenon.

Key words: seborrheic keratosis, flat wart, puber