Abstract: Objective: To assess the value of high-frequency ultrasound and Shear Wave ultrasound elastography in the diagnosis of Basal Cell Carcinoma (BCC). Methods: Patients with black skin space-occupying lesions in the clinical dermatology department of our hospital who agreed to undergo ultrasound examination and surgical treatment were collected from March 2017 to March 2019. Results: One hundred and eight patients were collected. 62 patients with BCC and 46 patients with other diseases were confirmed by biopsy. The diagnostic coincidence rate was 98.15% of high-frequency ultrasound elastography. The images of basal cell carcinoma lesions is mainly characterized by skin thickening, rough or varying degrees of epidermal defect changes，multiple strong punctate echoes (without of sound shadow), a slight attenuation in the rear, and the internal blood flow signals vary. The average Young’s modulus is (36.3±8.3) kpa, and the elastic strain ratio is about（7.4±3.2) with the surrounding normal tissue. Conclusion: High frequency ultrasound shear wave elastography has high diagnostic ability for basal cell carcinoma of skin.

Key words: basal cell carcinoma, high-frequency ultrasound, elasticity imaging techniques, Young’s modulus, seborrheic keratosis