Abstract: Objective：To characterize the clinical features of scrub typhus. Methods：Clinical data in 45 patients with scrub typhus diagnosed from August 2012 to March 2016 were analyzed retrospectively. Results: Incubation period was 3 weeks in the series of the patients. The main clinical manifestations included fever in 45 patients (100.00%), headache in 13 (28.89%), myalgia 25 (55.56%), cutaneous manifestations 45 (100.00%), fatigue 32 (71.11%) and gastrointestinal symptoms 16 (35.55%).?Macular/maculopapular lesions on the trunk and limbs were seen in 37 patients (82.22%). The most characterized skin lesion was black eschar, mainly in chest in 13 patients (28.89%), abdomen in 11 (24.44%), axillae 5 (11.11%) and perineum 4 (8.89%). ?Conclusion: The clinical manifestations of scrub typhus varies and the most useful clue in the diagnosis of scrub typhus is eschar lesion.

Key words: scrub typhus, clinical features, retrospective analysis