白介素-17家族与银屑病

Abstract

Abstract:

The members of interleukin-17（IL-17）family consist of six ligands (IL-17A to IL-17F), and five receptors (IL-17RA to IL-17RE). Each ligand binds to the corresponding receptor complex and then exerts biological effects. IL-17 can fight extracorporeal pathogens by activating host defense pathways, promoting release of antimicrobial peptides, chemokines and pro-inflammatory cytokines. Due to the increase in the expression of pro-inflammatory cytokines and chemokines, IL-17 has been proved to be associated with the pathogenesis of some inflammatory and autoimmune diseases. The relationship between the members of IL-17 family and the pathogenesis of psoriasis were reviewed in this paper.

Key words: IL-17')">

IL-17, psoriasis

YIN Li, YIN Zhiqiang..

Interleukin-17 family and psoriasis [J].China Journal of Leprosy and Skin Diseases, 2017, 33(1): 59-61.

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Interleukin-17 family and psoriasis

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