FLG,特应性皮炎,银屑病,寻常型鱼鳞病 ," /> FLG,特应性皮炎,银屑病,寻常型鱼鳞病 ,"/> FLG,atopic dermatitis,psoriasis,ichthyosis vulgaris ,"/> <p class="MsoNormal"> Update of FLG gene and related diseases

China Journal of Leprosy and Skin Diseases ›› 2017, Vol. 33 ›› Issue (2): 117-120.

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Update of FLG gene and related diseases

LI Jinghui12, YOU Jiabao12, LIU Hong12, ZHANG Furen12   

  1. 1. Shandong Provincial Hospital for Skin Diseases, Affiliated to Shandong University, Jinan 250022, China; 2. Shandong Provincial Institute of Dermatology and Venereology, Shandong Academy of Medical Sciences Jinan 250022, China

  • Online:2017-02-15 Published:2018-12-14
  • Contact: LI Jinghui, E-mail: hh3903@sina.com

Abstract:

Filaggrin gene (FLG), which encodes profilaggrin, is located on human chromosome1q21.3. FLG is associated with the epidermal barrier and the cell differentiation. The polymorphism of FLG gene is closely associated with atopic dermatitis, psoriasis, ichthyosis vulgaris as well as other diseases. The FLG gene and related diseases were reviewed in this article.

Key words: FLG')">

FLG, atopic dermatitis, psoriasis, ichthyosis vulgaris