Abstract: Large numbers of colonizing complex and diversity microorganisms are on the skin surface, including bacteria, archaea, fungi, viruses and mites. The knowledge of microorganisms is known more and more as the development of modern sequenc-based approaches. The update of the knowledge about microorganisms on the healthy skin and atopic dermatitis, psoriasis, acne, and rosacea lesions is reviewed in this article.

Key words: skin microbiome, modern sequence-based approaches, skin diseases, metagenomics