神经酰胺与相关皮肤病的研究进展

doi:10.12144/zgmfskin202010626

Abstract

Abstract: Ceramide (Cer) consist of a long-chain sphingosine or a related long chain base linked to fatty acid. As an important lipid in epidermis, ceramide doesn't only contribute to the formation of skin barrier, but also plays an important role in the regulation of skin immunity, cell cycle, differentiation and apoptosis. The abnormal anabolism of ceramide is related to many skin diseases, such as atopic dermatitis and psoriasis. The update of the ceramide and related dermatosis is reviewed in this paper.

Key words: ceramide, skin barrier, skin diseases

LIU Yunyi, ZHANG Jiawen, LIU Zijing, WANG Xiaoyan, LIU Yixuan, JIANG Peiyu, XU Yang. Update of the ceramide and related dermatosis[J].China Journal of Leprosy and Skin Diseases, 2020, 36(10): 626-630.

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Update of the ceramide and related dermatosis

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