抗MDA5抗体阳性临床无肌病性皮肌炎一例并文献复习

doi:10.12144/zgmfskin202407494

Abstract

Abstract: Clinical amyopathic dermatomyositis with anti-MDA5 antibody positive is a special type of dermatomyositis. Interstitial lung disease is the main pulmonary complication of this disease, which is rare in China. We reports a case of clinical amyopathic dermatomyositis with anti-MDA5 antibody positive and reviews the literature. A 67-year-old female presented with multiple erythematous plaques on the face and neck, back of the shoulders and hands, with aching and weakness of the limbs for 50 days. Myositis antibody spectrum showed anti-MDA5 antibody IgG(++++), anti-SRP antibody IgG (+), anti-SSA/Ro-52 antibody(+). Chest CT revealed bilateral interstitial lung fibrosis with infection. The diagnosis of clinical amyopathic dermatomyositis (anti-MDA5 antibody-positive) was made.

Key words: anti-MDA5 antibody')">">anti-MDA5 antibody, clinical amyopathic dermatomyositis

MI Qian, MENG Zhaoying, YANG Jinliang. Clinical amyopathic dermatomyositis with anti-MDA5 antibody positive: a case report and literature review[J].China Journal of Leprosy and Skin Diseases, 2024, 40(7): 494-498.

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URL: http://www.zgmfskin.com/EN/10.12144/zgmfskin202407494

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Clinical amyopathic dermatomyositis with anti-MDA5 antibody positive: a case report and literature review

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