中国麻风皮肤病杂志 ›› 2022, Vol. 38 ›› Issue (9): 636-637.doi: 10.12144/zgmfskin202209636

• 病例报告 • 上一篇    下一篇

Wong型无肌病性皮肌炎一例

郑铭,Aliza Paudyal,吕小岩   

  1. 四川大学华西医院皮肤性病科，四川成都，610041
  • 出版日期:2022-09-15 发布日期:2022-07-13

Wong-type amyopathic dermatomyositis: a case report

ZHENG Ming, PAYDYAL Aliza, LYU Xiaoyan   

  1. Department of Dermatology and Venereology, Sichuan University, West China Hospital, Chengdu 610041,China
  • Online:2022-09-15 Published:2022-07-13

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摘要： 患者，女，72岁。头面颈部红斑、丘疹伴瘙痒16年，日晒后加重。实验室检查示：抗TIF1-γ抗体阳性。额部皮肤组织病理表现为表皮角化过度，局灶性角化不全和界面皮炎改变。结合患者典型皮肌炎皮肤表现和额部毛发红糠疹样皮疹，诊断为Wong型无肌病性皮肌炎。给予阿维A、海棠合剂、1%吡美莫司乳膏等治疗，病情逐渐好转。

关键词: 皮肌炎, 毛发红糠疹

Abstract: A 72-year-old female presented with skin rashes and pruritus on the face and neck for 16 years, and skin lesions got worsened after sun exposure. The myositis specific autoantibodies panel showed a positive anti-TIF1-γ antibody. Skin biopsy taken from the forehead revealed histopathologic changes of hyperkeratosis, focal parakeratosis and interface dermatitis. Based on the classic manifestations of dermatomyositis and the presence of pityriasis rubra pilaris-like eruptions on the forehead, the diagnosis of Wong-type amyopathic dermatomyositis was made. A treatment with oral acitretin and Haitang Heji was initiated, combined with topical pimecrolimus cream and the patient responded well to the therapy.

Key words: dermatomyositis, pityriasis rubra pilaris