中国麻风皮肤病杂志 ›› 2024, Vol. 40 ›› Issue (5): 365-370.doi: 10.12144/zgmfskin202405365

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外泌体在炎症性皮肤疾病中的作用研究进展

邓皓月,黎静宜   

  1. 四川大学华西医院皮肤性病科，四川成都，610041
  • 出版日期:2024-05-15 发布日期:2024-04-22

Research progress on the role of exosomes in inflammatory skin diseases

DENG Haoyue, LI Jingyi   

  1. Department of Dermatology, West China Hospital, Sichuan University, Chengdu 610041, China
  • Online:2024-05-15 Published:2024-04-22

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摘要： 外泌体是包含蛋白质、脂质、核酸等物质的直径为30~150 nm的细胞外囊泡，它是参与皮肤免疫稳态和病理改变的关键因子，在炎症性皮肤疾病的发生发展中发挥调控作用。本文就外泌体在相关炎症性皮肤疾病发病机制中的作用做一综述，探讨外泌体在炎症性皮肤疾病治疗中的价值。

关键词: 外泌体, 炎症性皮肤疾病

Abstract: Exosomes are cell-derived vesicles ranging in size from 30-150nm and containing proteins, lipids, nucleic acids and other substances. They are a crucial factor involved in the maintenance of skin immune homeostasis and pathologic changes, regulating the onset and development of inflammatory skin diseases. In this paper, we review the role of exosomes in the pathogenesis of related inflammatory skin diseases and explores the value of exosomes in the treatment of inflammatory skin diseases.

Key words: exosome, inflammatory skin disease