中国麻风皮肤病杂志 ›› 2025, Vol. 41 ›› Issue (3): 207-209.doi: 10.12144/zgmfskin202503207

• 病例报告 • 上一篇    下一篇

结节性皮肤狼疮黏蛋白病一例

于越乾1,2,陈声利1,2,周桂芝1,2,刘红1,2,张福仁1,2   

  1. 1山东第一医科大学附属皮肤病医院，山东济南，250022；2山东省皮肤病性病防治研究所，山东济南，250022
  • 出版日期:2025-03-15 发布日期:2025-03-03

Nodular cutaneous lupus mucinosis: a case report

YU Yueqian1,2, CHEN Shengli1,2, ZHOU Guizhi1,2, LIU Hong1,2, ZHANG Furen1,2   

  1. 1 Hospital for Skin Diseases, Shandong First Medical University, Jinan 250022, China; 2 Shandong Provincial Institute of Dermatology and Venereology, Shandong Academy of Medical Sciences, Jinan 250022, China
  • Online:2025-03-15 Published:2025-03-03

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摘要： 结节性皮肤狼疮黏蛋白病（nodular cutaneous lupus mucinosis，NCLM）又名丘疹结节性黏蛋白病，临床表现为红斑狼疮相关的丘疹和结节,组织病理为真皮胶原纤维间黏蛋白弥漫性沉积。该病罕见，于1954年首次被报道，目前中文病例报道共9篇。本文报道1例NCLM青年患者，并回顾国内外报道的NCLM病例特点。

关键词: 结节性皮肤狼疮黏蛋白病, 系统性红斑狼疮, 皮肤型红斑狼疮

Abstract: Nodular cutaneous lupus mucinosis (NCLM) is also known as papule nodular mucins disease. The clinical manifestations are papules and nodules associated with lupus erythematosus, pathology of dermal collagen fibers mucins diffuse deposits. This rare disease was first reported in 1954, and 9 cases have been reported in China. The complete clinical information, laboratory and histopathological results, diagnosis and treatment plan and prognosis of a young patient with NCLM were reported, and the characteristics of NCLM cases reported at home and abroad were reviewed.

Key words: nodular cutaneous lupus mucinosis, systemic lupus erythematosus, lupus erythematosus skin type