中国麻风皮肤病杂志 ›› 2026, Vol. 42 ›› Issue (2): 124-127.doi: 10.12144/zgmfskin202602124

• 病例报告 • 上一篇    下一篇

肛管鳞癌阴囊转移一例

李靖欢1,田怡2,艾东方1,3,刘远1，3,冯世军1，3   

  1. 1河北医科大学附属沧州市中心医院皮肤科，河北沧州，061000； 2国家儿童医学中心首都医科大学附属北京儿童医院皮肤科，北京，100045； 3沧州市中心医院皮肤科，河北沧州，061000
  • 出版日期:2026-02-15 发布日期:2026-01-28

Scrotal metastatic from anal canal squamous cell carcinoma: a case report

LI Jinghuan1, TIAN Yi2, AI Dongfang1,3, LIU Yuan1,3, FENG Shijun1,3   

  1. 1 Cangzhou Central Hospital Affiliated to Hebei Medical University, Cangzhou 061000, China; 2 Department of Dermatology, Beijing Children's Hospital, Capital Medical University, National Center for Children's Health, Beijing 100045, China; 3 Cangzhou Central Hospital, Cangzhou 061000, China
  • Online:2026-02-15 Published:2026-01-28

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摘要： 患者，男，63岁，阴囊肿物1月余，呈类圆形结节，边界较清，活动度差，表面可见血痂。实验室检查：梅毒快速血浆反应素阴性，梅毒螺旋体抗体(ELISA): 20.33 S/CO；HIV抗体阳性。皮损组织病理符合高分化鳞状细胞癌。患者诉近8个月偶有肛周不适感，直肠指检于肛管5-6点钟方向触及一质硬肿物，穿刺活检示鳞状细胞癌。盆腔磁共振平扫同时增强考虑肛管鳞癌，双侧腹股沟区肿大淋巴结，考虑转移。请多科室联合会诊后，转入肿瘤科进行相关治疗，但患者后续未规律接受治疗，于确诊后一年死亡。

关键词: 鳞癌, 阴囊转移, 肛管鳞癌, HIV, HPV

Abstract: A 63-year-old male presented with a scrotal mass for more than 1 month. The lesion was an oval nodule with relatively clear borders, poor mobility, and blood crusts on the surface. Laboratory examinations showed RPR test was negative, Treponema pallidum antibody (ELISA): 20.33 S/CO, HIV antibody was positive. Histopathological features of the skin lesion were consistent with well-differentiated squamous cell carcinoma. The patient reported occasional perianal discomfort in the recent 8 months. Digital rectal examination revealed a hard mass at the 5-6 o'clock position of the anal canal, and needle biopsy confirmed squamous cell carcinoma. Pelvic magnetic resonance imaging (MRI) with plain and enhanced scans suggested anal canal squamous cell carcinoma, accompanied by enlarged lymph nodes in the bilateral inguinal regions, which were considered metastatic. After multidisciplinary consultation, the patient was transferred to the department of medical oncology for relevant treatment. However, the patient failed to receive regular treatment thereafter and succumbed one year after diagnosis.

Key words: squamous cell carcinoma, scrotal metastasis, anal canal squamous cell carcinoma, HIV, HPV