中国麻风皮肤病杂志 ›› 2018, Vol. 34 ›› Issue (11): 669-671.

• 短篇论著 • 上一篇    下一篇

获得性反应性穿通性胶原病九例临床及病理分析

吕 静 肖 沙 赵 鹏 阎 衡 黄 燕 郝 进 高 涛   

  1. 重庆市第一人民医院 重庆市中医院(道门口院部)皮肤科,重庆,400011
  • 出版日期:2018-11-15 发布日期:2018-12-01
  • 通讯作者: 高涛,E-mail: 171942413@qq.com

Clinicopathology analyses of 9 cases with acquired reactive perforating collagenosis

LYU Jing, XIAO Shao, ZHAO Peng, YAN Heng, HUANG Yan, HAO Jin, GAO Tao   

  1. Department of Dermatology, the First People’S Hospital, Traditional Chinese Medicine Hospital, Chongqing 400011, China
  • Online:2018-11-15 Published:2018-12-01
  • Contact: GAO Tao, E-mail: 171942413@qq.com

摘要: 对2015年1月至2017年12月我院9例获得性反应性穿通性胶原病临床资料和组织病理进行回顾性分析。其中男女比例为1:1.25,平均发病年龄53.89岁,平均病程9.67个月,临床皮损形态多样,组织病理均可见变性的胶原纤维穿出表皮,有8例患者(88.9%)伴有糖尿病,2例患者(25%)伴有高血压。9例患者均被误诊为其他疾病,最易误诊为结节性痒疹 和湿疹或湿疹样皮炎 ,其余依次是皮肤血管炎 、坏疽性脓皮病 、皮肤溃疡、真菌感染、神经性皮炎、痒疹性大疱性类天疱疮、大疱性表皮松解症、扁平苔藓,均为1例次。

关键词: 反应性穿通性胶原病, 临床, 病理

Abstract: Clinical and pathological data of 9 cases with acquired reactive perforating collagenosis from Jan.2015 to Dec.2017 were retrospectively analyzed. The ratio of male to female was 1:1.25. The average age at onset was 53.89 years old. The average duration was 9.67 months. The biopsy shows denatured collagen fibers within the epidermis. There were 8 cases (88.9%) with diabetes, 2 (25%) with hypertension. All 9 patients were misdiagnosed as other diseases, including prurigo nodular , eczema , cutaneous vasculitis , pyoderma gangrenosum skin?ulcers , mycotic infection , neurodermitis prurigo bullous pemphigoid , epidermolysis bullosa, ?lichen planus(1 time).

Key words: acquired reactive perforating collagenosis, clinic, pathology

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