Abstract: A 28-year-old male presented with pruritus all over his body for 11 years, red papules and plaques on head, neck, trunk and arms with peripheral eosinophilia for 5 years, and alopecia for 2 years. Peripheral blood eosinophilic cell count was 11088/μL. Histopathological findings showed a mixed perifollicular infiltration which was composed mainly of irregular-shaped atypical lymphocytes and scattered eosinophils. Immunohistochemical staining indicated that the majority of infiltrated lymphocytes were CD4+ lymphocytes. TCR gene rearrangement showed TCRδ and TCRγ were positive. The diagnosis of folliculotropic mycosis fungoides was made. The lesions were improved after 7 weeks' treatment of intramuscular injections of recombinant interferon α-2b, oral acitretin, methotrexate, prednisone and topical corticosteroids cream.

Key words: mycosis fungoides, folliculotropic