Abstract: The efficacy of traditional treatment for pityriasis rubra pilaris, including retinoids, methotrexate, cyclosporine, topical glucocorticoids, and physical therapy, is not satisfactory. The foreign research reported secukinumab was used for treatment of pityriasis rubra pilaris and obtained good efficacy, but there was no report in China. We report a case with pityriasis rubra pilaris successfully treated with secukinumab and review the related literature review. 

Key words: pityriasis rubra pilaris, treatment, biological agents, secukinumab