Abstract: Objective: To assess the curative effect of supramolecular salicylic acid combined with adjusted decoction of liangxuewuhua in treating patients with rosacea. Methods: The patients with rosacea were selected from the outpatient department in our hospital from March to September 2022, and they were divided into treatment group and control group randomly. The patients in the additionally control group was treated with adjusted decoction of liangxuewuhua, the patients in the treatment group were given 30% supramolecular salicylic acid irradiation, once every 2 weeks. Human-like collagen dressing was applied after supramolecular salicylic acid in treatment group once a day during the first week, and then changed to once every other day after 1 week. All the patients were treated for 8 weeks. Results: A total of 60 cases of rosacea were treated, including 30 cases in the treatment group and 30 cases in the control group. During the treatment, 2 cases in control group dropped out. After 8 weeks,the effective rate of the treatment group was 93.33%, while that of the control group was 67.86%, with a significant difference (P<0.05). Conclusions: Supramolecular salicylic acid combined with adjusted decoction of liangxuewuhua in the treatment of rosacea is effective,which is superior to the treatment of traditional Chinese medicine alone.

Key words: rosacea, supramolecular salicylic acid, decoction of liangxuewuhua