China Journal of Leprosy and Skin Diseases ›› 2024, Vol. 40 ›› Issue (1): 50-52.doi: 10.12144/zgmfskin202401050

• Case Reports • Previous Articles     Next Articles

Refractory SAPHO syndrome treated with tofacitinib: a case report

SAI Wenwen1，2, WANG Guangjin1，2   

  1. 1 Hospital for Skin Diseases, Shandong First Medical University, Jinan 250022, China; 2 Shandong Provincial Institute of Dermatology and Venereology, Shandong Academy of Medical Sciences, Jinan 250022, China
  • Online:2024-01-15 Published:2023-12-25

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Abstract: We report a case of refractory SAPHO syndrome in which the disease could not be controlled by traditional drugs such as methotrexate and aveloxan capsules. After 6 weeks of maintenance treatment with adalimumab and echizumab, the disease remained uncontrolled.The rash completely disappeared,smooth new nail proximal to the toenail, no pressure pain in the sternoclavicular joint,after 75 days of treatment with the JAK inhibitor tofacitab.

Key words: tofacitinib, refractory SAPHO syndrome, Janus kinase inhibitor