China Journal of Leprosy and Skin Diseases ›› 2024, Vol. 40 ›› Issue (12): 875-877.doi: 10.12144/zgmfskin202412875

• Case Reports • Previous Articles     Next Articles

Corneal leucoma after unilateral syphilitic stromal keratitis complicated with neurosyphilis：a case report

XU Yuxuan1, XIA Wei2, XU Yating1, LI Jingjing1, WANG Qianqiu3, LI Shanshan1, DAI Jun1, WU Minzhi1   

  1. 1 Department of Dermatology, The Fifth People's Hospital of Suzhou, Suzhou 215000, China; 2 Ophthalmology Department, The First Affiliated Hospital of Soochow University, Suzhou 215000, China; 3 Institute of Dermatology, Chinese Academy of Medical Sciences and Peking Union Medical College, Nanjing 210042, China
  • Online:2024-12-15 Published:2024-10-31

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Abstract: We report a rare case of corneal leucoma after unilateral syphilitic stromal keratitis complicated with neurosyphilis. A 30-year-old female presented with blurry vision on the right eye for 10 days. Serologically positive for syphilis. Cerebrospinal fluid tests are consistent with neurosyphilis. The patient was treated with penicillin sodium and methylprednisolone to prevent Jarisch-Herxheimer reaction. After the treatment, the patient's vision recovered, corneal scarring formed, and syphilitic indicators decreased. This paper reminds clinicians to strengthen the comprehensive evaluation of the nervous system of patients with ocular syphilis, and timely diagnosis and treatment.

Key words: syphilitic stromal keratitis, corneal leucoma, ocular syphilis, Goldmann-Witmer coefficient, neurosyphilis