China Journal of Leprosy and Skin Diseases ›› 2022, Vol. 38 ›› Issue (4): 238-242.doi: 10.12144/zgmfskin202204238

• Case Reports • Previous Articles     Next Articles

Dapsone monotherapy in the treatment of rheumatoid neutrophilic dermatitis: a case report

WANG Ziyuan, ZHANG Fan, ZHOU Guizhi, LIU Yongxia, LIU Hong, ZHANG Furen   

  1. Shandong Provincial Hospital for Skin Diseases & Shandong Provincial Institute of Dermatology and Venereology, Shandong First Medical University, Jinan 250022, China
  • Online:2022-04-15 Published:2022-02-10
  • Contact: LIU Hong, E-mail: hongyue2519@hotmail.com

Abstract: Rheumatoid neutrophilic dermatitis is a specific skin manifestation of severe rheumatoid arthritis. We report a case and review the literature. A 60-year-old man presented with dark red papules and blisters on the trunk and limbs for one month. He had a 7-year-history of rheumatoid arthritis. The features of laboratory tests and histopathological examination were in accordance with rheumatoid neutrophilic dermatitis. The patient had been treated with immunosuppressant and glucocorticoid for rheumatoid arthritis, and this time dapsone alone was selected. The laboratory tests returned to normal and the lesions were basically subsided after treatment for 2 weeks.

Key words: rheumatoid neutrophilic dermatitis, dapsone