特应性皮炎瘙痒机制研究进展

doi:10.12144/zgmfskin202510765

Abstract

Abstract: Atopic dermatitis is a chronic inflammatory skin disease characterized by intense pruritus and recurrent episodes. Pruritus is regarded as a core manifestation of atopic dermatitis, with an especially complex underlying mechanism. Recent studies have indicated that neuroimmune interactions and skin barrier dysfunction play key roles in atopic dermatitis-related pruritus. This paper reviews the the pruritus-related mechanisms and advances in therapeutic approaches.

Key words: atopic dermatitis, pruritus, neuroimmunity, skin barrier

SUN Jingyi, GAO Mingxuan, YAO Xinyu, ZHOU Lingxuan, ZHAO Jiahui. Advances in understanding the pruritic mechanisms of atopic dermatitis[J].China Journal of Leprosy and Skin Diseases, 2025, 41(10): 765-770.

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Advances in understanding the pruritic mechanisms of atopic dermatitis

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