Abstract: Linear IgA bullous dermatosis (LABD) is an autoimmune bullous diseases characterized by continuous deposition of IgA autoantibody in the basement membrane zone (BMZ). It may be related to genetics, drugs, inflammatory diseases and tumor. The diagnosis of LABD should be confirmed by clinical manifestation,histopathological and immunofluorescence examination. Dapsone is the first line therapy for LABD. Biological agents have also been reported to treat the disease in recent years. This review summarizes epidemiological features, pathogenesis, clinical manifestations, laboratory examination, diagnosis and treatment of LABD.

Key words: linear IgA bullous dermatosis, diagnosis, therapy