Abstract:

Pyoderma gangrenosum（PG）is a rare neutrophil dermatosis caused by abnormal neutrophil aggregation after an inflammation cascade, mainly manifested by aseptic neutrophil infiltration and systemic inflammation . The latest research showed that drugs can cause PG, but there are few related reports and clinicians' understanding of it is relatively insufficient. PG is often misdiagnosed as difficult-to-heal ulcer and treated with debridement in clinical practice. Debridement will directly lead to the spread and deterioration of the lesion. The correct diagnosis of PG is very important for the treatment and prognosis of the disease. The update of diagnosis and treatment of pyoderma gangrenosum is reviewed in this artical.

Key words: pyoderma gangrenosum, drugs, diagnosis, treatment