Abstract: A 33-year-old female presented with skin papules on her right calf for more than 30 years, accompanied by redness, swelling and pain for 3 months. Surgical excision was performed. Postoperative pathology showed that the tumor cells grew around the thin-walled vessels in a multi-layer concentric circle, and partial vascular lumen occlusion was visible. Immunohistochemistry showed ERG (vascular +), CD34 (vascular +), CD31 (vascular +), SMA (+), Desmin (-), H-Caldesmon (+). Myopericytoma was considered in combination with morphology and immunohistochemistry. Extensive excision was performed and skin grafts were performed.

Key words: myopericytoma, diagnosis, treatment