Abstract: Objective: To access the efficacy and safety of superficial X-ray combined with triamcinolone acetonide injection in the treatment of maxillofacial post-acne keloids. Methods: A retrospective analysis was performed on the clinical data of 26 patients with maxillofacial post-acne keloids who received superficial X-ray therapy combined with triamcinolone acetonide injection in our hospital from April 2022 to December 2022. Three independent dermatologists assessed efficacy, recurrence and adverse reactions, and the Wilcoxon signed-rank test was employed for hypothesis testing on paired pre- and post-treatment data.the t-test was employed for statistical data analysis. Results: Seven patients were lost to follow-up and nineteen patients were completed the whole observation. The VSS score was 8.68±1.60 before treatment and 4.68±1.10 at 6 months after treatment, with a statistically significant difference (Z=-3.86, P＜ 0.01). One year after treatment, 3 cases relapsed, with a remission rate of 84.21% (16/19). The main adverse reactions were radiation dermatitis and pigmentation. Conclusion: Superficial X-ray therapy combined with triamcinolone acetonide injection is safe and effective for treating maxillofacial post-acne keloids.

Key words: keloid, superficial X-ray, triamcinolone acetonide