中国麻风皮肤病杂志 ›› 2020, Vol. 36 ›› Issue (3): 155-157.doi: 10.12144/zgmfskin202003155

• 短篇论著 • 上一篇    下一篇

新生儿红斑狼疮三例并文献复习

卢丽清,倪昌雯,黄玲   

  1. 大理大学第一附属医院皮肤科，云南大理， 671000
  • 出版日期:2020-03-15 发布日期:2020-03-30
  • 通讯作者: 黄玲，E-mail：huanglingx@126.com

Neonatal lupus erythematosus: three cases report and literature review

LU Liqing, NI Changwen, HUANG Ling   

  1. Dermatology Department of the First Affiliated Hospital of Dali University, Dali 671000, China
  • Online:2020-03-15 Published:2020-03-30
  • Contact: HUANG Ling, E-mail：huanglingx@126.com

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摘要： 报道3例新生儿红斑狼疮并对相关文献进行复习。3例患儿皮损表现为红斑、丘疹，以面部为主，第2例患儿母亲有干燥综合症6年，第1例及第3例患儿母亲无结缔组织病史。患儿及其母亲抗核抗体、抗Ro/SSA抗体、抗La/SSB 抗体、抗Ro-52抗体均阳性。3例心电图检查均未见心脏传导阻滞，2例患儿伴肝损伤。均予泼尼松及对症治疗后病情好转。

关键词: 红斑狼疮, 新生儿

Abstract: Three cases of neonatal lupus erythematosus were reported and literature was reviewed. The more common lesions were manifested as erythema and papula on the face in the three patients. The second patient's mother had a history of Sjgren's syndrome for 6 years, and the other mothers had no history of connective tissue diseases. Serum ANA, anti-Ro/SSA, anti-La/SSB and Ro-52 antibodies were positive in the three infants and their mothers. Electrocardiography revealed no congenital heart block. Two had hepatic impairments. Symptoms subside after prednisone and symptomatic treatment.

Key words: lupus erythematosus, neonatal