中国麻风皮肤病杂志 ›› 2021, Vol. 37 ›› Issue (2): 65-68.doi: 10.12144/zgmfskin202102065

• 论著 • 上一篇    下一篇

2010-2019年山东省梅毒流行特征分析

刘健1,2,叶星2,3,槐鹏程2,刘殿昌2,初同胜2,李富容2,张福仁2,李士雪1   

  1. 1山东大学公共卫生学院，济南，250012；2山东第一医科大学附属皮肤病医院（山东省皮肤病医院，山东省皮肤病性病防治研究所），济南，250022；3山东第一医科大学，济南，250021
  • 出版日期:2021-02-15 发布日期:2021-02-02
  • 通讯作者: 李士雪，E-mail: shixueli@sdu.edu.cn

Epidemiological characteristics and trend of Syphilis infection in Shandong province, 2010 to 2019

LIU Jian1,2, YE Xing2,3, HUAI Pengcheng2, LIU Dianchang2, CHU Tongsheng2, LI Furong2, ZHANG Furen2, LI Shixue1   

  1. 1 School of Public Health, Shandong University, Jinan 250012, China; 2 Shandong Provincial Hospital for Skin Diseases & Shandong Provincial Institute of Dermatology and Venereology, Shandong First Medical University, Jinan 250022, China; 3 Shandong First Medical University, Jinan 250021, China
  • Online:2021-02-15 Published:2021-02-02
  • Contact: LI Shixue, E-mail: shixueli@sdu.edu.cn

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摘要： 目的：了解山东省梅毒流行特征及趋势，为梅毒防治措施的制定提供科学依据。方法：对2010-2019年山东省16个地级市报告的梅毒病例资料进行流行病学分析，描述梅毒报告病例的三间分布，计算发病率、构成比、年均增长率，采用χ2趋势检验分析梅毒的发病趋势。结果：山东省梅毒报告发病率由2010年6.15/105增至2019年20.24/105，呈逐年增长趋势（χ2=12475.40，P<0.01），年均增长率为14.15%。其中，隐性梅毒占比增长最快，由2010年的31.98%增至2019年的74.28%。高发地区为鲁东半岛的威海市、青岛市及鲁南地区的枣庄市，年均报告发病率在20/105以上。各年女性报告病例数均多于男性，男女性别比为0.89∶1。从年龄分布来看，20~35岁人群梅毒报告病例数占比最多，占总病例数的39.41%；60~79岁人群报告发病率增速最快，年均增长率为22.82%。20类职业中，农民报告病例数最多，占43.94%。结论：山东省梅毒报告发病率呈较快增长，其中隐性梅毒增长尤为迅速。需加强梅毒筛查和防治，特别是高发地区及高发人群。

关键词: 梅毒, 流行病学, 性传播感染

Abstract: Objective: To explore the characteristics and trends of syphilis infection in Shandong province, providing scientific evidence for the control strategy of syphilis. Methods: The data of the patients with syphilis from 16 prefecture-level cities in Shandong province from 2010 to 2019 were analyzed, including incidence, proportion, annual growth rate and distribution. Chi-square test was used to explore the incidence trend of syphilis. Results: The incidence of syphilis increased from 6.15 per 100 thousand in 2010 to 20.24 per 100 thousand in 2019, showing a year-on-year growth trend (χ2=12475.40, P<0.01), with an average annual growth rate of 14.15%. In particular, the cases of latent syphilis showed the fastest rate of growth, from 31.98% in 2010 to 74.28% in 2019. The high-incidence areas were Weihai, Qingdao in the eastern coastal area, and the Zaozhuang in the southern area, with an average annual incidence of more than 20 per 100 thousand person-years. The number of female patients was higher than that of males, with an average male/female ratio of 0.89∶1. The peak age was 20-35 years, accounting for 39.41%, and the incidence increased the fastest in the cases of 60-79 years, with an average annual growth rate of 22.82%. Of the 20 occupational groups, peasant was the most (43.94%). Conclusion: The incidence of syphilis, especially latent syphilis, in Shandong Province increase rapidly. It is necessary to strengthen the screening of syphilis, especially in the high incidence areas and high incidence population.

Key words: syphilis, epidemiology, sexually transmitted infections