中国麻风皮肤病杂志 ›› 2025, Vol. 41 ›› Issue (8): 620-625.doi: 10.12144/zgmfskin202508620

• 综述 • 上一篇    下一篇

从皮肤癣菌-宿主-微生态多维视角探析头癣发病机制

伍丹丹1，2,朱卿滢1，2,尹斌2   

  1. 1 川北医学院研究生院，四川南充，637000；2 成都市第二人民医院皮肤科，四川成都，610017
  • 出版日期:2025-08-15 发布日期:2025-08-01

Pathogenesis of tinea capitis from the multidimensional perspective of dermatophytes-host-microecology

WU Dandan1,2, ZHU Qingying1,2, YIN Bin2   

  1. 1 Graduate School of North Sichuan Medical College, Nanchong 637000, China; 2 Department of Dermatology, Chengdu Second People's Hospital, Chengdu 610017, China
  • Online:2025-08-15 Published:2025-08-01

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摘要： 头癣是由皮肤癣菌感染毛发和头皮引起的浅部真菌病，多发于儿童和绝经后妇女。其发病涉及皮肤癣菌的侵入机制，皮肤癣菌与宿主免疫的相互作用，以及头皮微生态失衡，尤其是皮脂腺功能改变和微生物群落紊乱对头癣发生发展的影响。本文从多方面综述头癣的发病机制，为开发新的预防和治疗策略提供科学依据。

关键词: 头癣, 皮肤癣菌, 免疫反应, 头皮微生态, 发病机制

Abstract: Tinea capitis is a superficial fungal infection of the hair and scalp caused by dermatophytes, which is more common in children and postmenopausal women. The pathogenesis of tinea capitis involves the invasion mechanism of dermatophytes, the interaction between dermatophytes and host immunity, and the influence of scalp microecological imbalance, especially the change of sebaceous gland function and microbial community disorder on the occurrence and development of tinea capitis. This paper review the pathogenesis of tinea capitis from various aspects, and provide scientific basis for the development of new prevention and treatment strategies.

Key words: tinea capitis, dermatophytes, immune response, scalp microecology, pathogenesis